abstract：PURPOSE:The cyclolignan picropodophyllin (PPP) efficiently blocks the activity of insulin-like growth factor-1 receptor (IGF-1R) and inhibits growth of uveal melanoma cells in vitro and in vivo. In this study, we aimed to investigate the efficiency of orally administered PPP on growth of uveal melanoma xenografts. Furt...

journal_title：Acta ophthalmologica

authors： Economou MA,Andersson S,Vasilcanu D,All-Ericsson C,Menu E,Girnita A,Girnita L,Axelson M,Seregard S,Larsson O

更新日期：2008-11-01 00:00:00

abstract：PURPOSE:The Pyhäjärvi Cataract Study aims to study demand for cataract surgery in the population of a rural town in Finland. METHODS:A random, population-based sample of 881 persons aged > or = 60 years were interviewed by telephone to obtain a Visual Function-14 (VF-14) score. A total of 294 persons were invited for ...

journal_title：Acta ophthalmologica

authors： Falck A,Kuoppala J,Winblad I,Tuulonen A

更新日期：2008-09-01 00:00:00

abstract：:Vitreomacular traction resulting from lacking, incomplete or anomalous posterior vitreous detachment is suspected to play a crucial role in the pathogenesis of different forms of age-related macular degeneration (AMD) along with the known mechanisms. It is probable that the fundamental pathomechanisms of AMD formation...

journal_title：Acta ophthalmologica

authors： Schulze S,Hoerle S,Mennel S,Kroll P

更新日期：2008-08-01 00:00:00

abstract：PURPOSE:Current evidence indicates that alteration in ocular blood flow may be relevant in open-angle glaucoma (OAG) patients independent of intraocular pressure (IOP). Presently, the lack of an adequate methodology capable of assessing all vascular beds limits the clinical role of blood flow parameters in glaucoma man...

journal_title：Acta ophthalmologica

authors： Januleviciene I,Sliesoraityte I,Siesky B,Harris A

更新日期：2008-08-01 00:00:00

abstract：PURPOSE:To evaluate the ability of ultrasound biomicroscopy (UBM) to detect abnormalities in the zonular apparatus in unaffected eyes of patients with clinically unilateral exfoliation syndrome (XFS) using a standardized grading system. METHODS:The affected and unaffected eyes of 17 patients with clinically unilateral...

journal_title：Acta ophthalmologica

authors： Sbeity Z,Dorairaj SK,Reddy S,Tello C,Liebmann JM,Ritch R

更新日期：2008-08-01 00:00:00

abstract：PURPOSE:To investigate the distribution of intraocular pressure (IOP) measured by Goldmann applanation tonometry (GAT) and factors correlating with IOP, with special attention to age, in a large sample of ophthalmologically normal Japanese subjects. METHODS:A total of 7313 subjects (2847 male, 4466 female) were select...

journal_title：Acta ophthalmologica

authors： Fukuoka S,Aihara M,Iwase A,Araie M

更新日期：2008-06-01 00:00:00

abstract：PURPOSE:To test the expanded polytetrafluoroethylene (ePTFE) as a new adjuvant in trabeculectomy. METHODS:Consecutive glaucoma surgical inpatients were observed at the Department of Ophthalmology of Palermo University. Sixty patients (60 eyes) were randomly assigned to undergo trabeculectomy (T), trabeculectomy with m...

journal_title：Acta ophthalmologica

authors： Cillino S,Zeppa L,Di Pace F,Casuccio A,Morreale D,Bocchetta F,Lodato G

更新日期：2008-05-01 00:00:00

abstract：PURPOSE:This study aimed to investigate the retinal thickness analyser (RTA) as a means to identify the presence of cystoid macular oedema (CMO) in children with uveitis, whether the course of CMO can be monitored using this method, and whether there is a trend towards a correlation between macular oedema and visual ac...

journal_title：Acta ophthalmologica

authors： Maca SM,Garhofer G,Kiss C,Barisani-Asenbauer T

更新日期：2008-05-01 00:00:00

abstract：PURPOSE:To assess the predictive value of optical coherence tomography (OCT) mapping of retinal thickness and intraretinal morphological changes after macular grid for diffuse diabetic macular oedema (DMO). METHODS:We carried out a prospective, non-controlled, case series study, in which 28 consecutive eyes with previ...

journal_title：Acta ophthalmologica

authors： Soliman W,Sander B,Soliman KA,Yehya S,Rahamn MS,Larsen M

更新日期：2008-05-01 00:00:00

abstract：PURPOSE:To evaluate the effect of intravitreal injections of triamcinolone acetonide (IVTA) combined with panretinal photocoagulation (PRP) on visual acuity (VA) and foveal thickness in patients with concomitant high-risk proliferative diabetic retinopathy (PDR) and clinically significant macular oedema (CSMO). METHOD...

journal_title：Acta ophthalmologica

authors： Margolis R,Singh RP,Bhatnagar P,Kaiser PK

更新日期：2008-02-01 00:00:00

abstract：PURPOSE:The clinical use and comparison of two recently developed A-scan ultrasound devices. METHODS:The same investigator determined central corneal thickness (CCT), anterior chamber depth (ACD) and axial length (AL) with an OcuScan RxP (Alcon, Forth Worth, Texas, USA) and an AL-2000 (Tomey, Erlangen, Germany) ultras...

journal_title：Acta ophthalmologica

authors： Sohajda Z,Papp J,Berta A,Módis L

更新日期：2008-02-01 00:00:00